Pfam Domains mapped on to the structure: 2EPI

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01910	Domain of unknown function DUF77	PF01910	PF01910

Conserved Domain Database Superfamily Annotations: 2EPI

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2EPI	206972	cl00307	DUF77	superfamily - -

Structural Details of PDB entry 2EPI PDBid Chains Hinge Swapped Domain 2EPI A,D,C,B A:83-86,D:83-86,C:83-86,B:83-86 A:87-98,D:87-98,C:87-98,B:87-98 Swapped-domain interface residues and interactions: Chains Residues A 23, 26, 27, 44, 93, 94, 96, 97, 98, B 23, 27, 44, 90, 93, 94, 96, 97, Non-swapped-domain interface residues and interactions: Chains Residues A 8, 10, 12, 14, 20, 21, 30, 42, 43, 45, 48, 77, 79, 81, 83, 85, 86, 99, B 8, 10, 12, 20, 21, 26, 30, 34, 42, 43, 45, 48, 77, 79, 81, 83, 85, 86,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2EPI

B:2EPI

C:2EPI

D:2EPI

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2EPI.ali
atm file:	2EPI.atm
cof file:	2EPI.cof
hbd file:	2EPI.hbd
html file:	2EPI.html
pdb file:	2EPI.pdb
ps file:	2EPI.ps
psa file:	2EPI.psa
rtf file:	2EPI.rtf
sst file:	2EPI.sst
tem file:	2EPI.tem