Pfam Domains mapped on to the structure: 2EIW
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00171
Aldehyde dehydrogenase family
PF00171
PF00171
Conserved Domain Database Superfamily Annotations: 2EIW
Structural Details of PDB entry 2EIW
Structural Details of PDB entry 2EIW
PDBid Chains Hinge Swapped Domain
2EIW
A,B
A:152-156,B:152-156;A:171-176,B:171-176
A:157-170,B:157-170
Swapped-domain interface residues and interactions:
Chains Residues
A
157 , 158 , 159 , 160 , 162 , 165 , 166 , 167 , 168 , 170 , 481 , 482 , 483 ,
B
157 , 158 , 159 , 160 , 162 , 165 , 166 , 167 , 168 , 170 , 481 , 482 , 483 ,
Non-swapped-domain interface residues and interactions:
Chains Residues
A
6 , 8 , 91 , 144 , 151 , 154 , 171 , 172 , 266 , 269 , 270 , 273 , 274 , 275 , 280 , 281 , 282 , 283 , 284 , 287 , 442 , 454 , 461 , 462 , 463 , 465 , 466 , 467 , 468 , 469 , 471 , 472 , 473 , 479 , 484 , 488 , 489 , 490 , 492 , 493 , 494 , 496 , 499 , 500 , 501 , 504 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 ,
B
6 , 8 , 91 , 92 , 144 , 151 , 154 , 172 , 266 , 269 , 270 , 273 , 274 , 275 , 280 , 281 , 282 , 283 , 284 , 287 , 442 , 454 , 461 , 463 , 465 , 466 , 467 , 469 , 471 , 472 , 473 , 479 , 484 , 488 , 489 , 490 , 492 , 493 , 494 , 496 , 499 , 500 , 501 , 504 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 ,
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
