Pfam Domains mapped on to the structure: 2E2M

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF08534	Redoxin	PF08534	PF08534

Conserved Domain Database Superfamily Annotations: 2E2M

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2E2M	48565	cd03016	PRX_1cys -	cl00388
2	2E2M	212209	cl00388	Thioredoxin_like	superfamily - -
3	2E2M	212209	cl00388	Thioredoxin_like	superfamily - -

Structural Details of PDB entry 2E2M PDBid Chains Hinge Swapped Domain 2E2M A,B A:146-151,B:146-151 A:152-243,B:152-245 Swapped-domain interface residues and interactions: Chains Residues A 46, 47, 48, 49, 52, 56, 146, 147, 148, 149, 150, 153, 156, 157, 160, 161, 164, 170, 171, 172, 173, 174, 177, 178, 179, 180, 181, 182, 183, 186, 189, 206, 208, 209, 211, 212, 214, 227, 230, 231, 233, 234, 235, 236, 237, 240, 241, 242, 243, B 48, 49, 52, 56, 146, 147, 148, 149, 150, 153, 156, 157, 160, 161, 170, 171, 172, 173, 174, 177, 178, 179, 180, 181, 182, 183, 186, 189, 206, 208, 209, 211, 212, 214, 227, 230, 231, 233, 234, 235, 236, 237, 240, 241, 242, Non-swapped-domain interface residues and interactions: Chains Residues A 4, 5, 7, 8, 51, 55, 59, 60, 88, 92, 93, 114, 115, 116, 124, 138, 139, 140, 141, 142, 143, 144, B 5, 7, 8, 46, 51, 55, 59, 60, 88, 92, 93, 114, 116, 124, 138, 139, 140, 141, 142, 143, 144,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	SER(207)CYS,
B	No mutation	No mutation	No mutation	SER(207)CYS,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2E2M

B:2E2M

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2E2M.ali
atm file:	2E2M.atm
cof file:	2E2M.cof
hbd file:	2E2M.hbd
html file:	2E2M.html
pdb file:	2E2M.pdb
ps file:	2E2M.ps
psa file:	2E2M.psa
rtf file:	2E2M.rtf
sst file:	2E2M.sst
tem file:	2E2M.tem