Pfam Domains mapped on to the structure: 2E2G
Conserved Domain Database Superfamily Annotations: 2E2G
Structural Details of PDB entry 2E2G
Structural Details of PDB entry 2E2G
PDBid
Chains
Hinge
Swapped Domain
2E2G
F,A
F:146-151,A:146-151
F:152-245,A:152-245
Swapped-domain interface residues and interactions:
Chains
Residues
A
46 , 47 , 48 , 49 , 52 , 56 , 146 , 147 , 148 , 149 , 150 , 153 , 156 , 157 , 160 , 161 , 170 , 171 , 172 , 173 , 174 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 186 , 189 , 206 , 208 , 209 , 211 , 212 , 214 , 227 , 230 , 231 , 233 , 234 , 235 , 236 , 237 , 240 , 241 , 242 , 245 ,
F
46 , 47 , 48 , 49 , 52 , 56 , 146 , 147 , 148 , 149 , 150 , 153 , 156 , 157 , 160 , 161 , 170 , 171 , 172 , 173 , 174 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 186 , 189 , 206 , 208 , 209 , 211 , 212 , 214 , 227 , 230 , 231 , 233 , 234 , 235 , 236 , 237 , 240 , 241 , 242 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
4 , 5 , 7 , 8 , 51 , 55 , 59 , 60 , 88 , 92 , 93 , 114 , 116 , 124 , 138 , 139 , 140 , 141 , 142 , 143 , 144 ,
F
4 , 5 , 7 , 8 , 51 , 55 , 59 , 60 , 88 , 92 , 93 , 114 , 124 , 138 , 139 , 140 , 141 , 142 , 143 , 144 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
F No mutation No mutation No mutation SER(207)CYS,
A No mutation No mutation No mutation SER(207)CYS,
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: