Pfam Domains mapped on to the structure: 2DD8

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	H	PF13927	Immunoglobulin domain	PF13927	PF13927
2	H	PF13927	Immunoglobulin domain	PF13927	PF13927
3	L	PF13895	Immunoglobulin domain	PF13895	PF13895
4	L	PF13895	Immunoglobulin domain	PF13895	PF13895
5	L	PF13927	Immunoglobulin domain	PF13927	PF13927
6	L	PF13927	Immunoglobulin domain	PF13927	PF13927
7	S	PF09408	Spike receptor binding domain	PF09408	PF09408

Conserved Domain Database Superfamily Annotations: 2DD8

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2DD8	150170	Spike_rec_bind	superfamily	C -

Structural Details of PDB entry 2DD8 PDBid Chains Hinge Swapped Domain 2DD8 H,L H:42-46,L:41-45 H:2-41,L:2-40 Swapped-domain interface residues and interactions: Chains Residues H 39, 98, 99, 100, L 32, 34, 36, 38, Non-swapped-domain interface residues and interactions: Chains Residues H 44, 45, 47, 60, 91, 95, 96, 101, 103, 122, 123, 124, 125, 128, 129, 137, 141, 143, 144, 164, 166, 167, 168, 169, 171, 172, 177, 179, 181, 209, 214, 216, L 43, 44, 46, 50, 87, 89, 91, 95, 96, 98, 117, 119, 120, 121, 122, 123, 124, 125, 128, 130, 132, 134, 136, 138, 161, 163, 166, 168, 175, 176, 177, 179, 181, 212,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2DD8

L:2DD8

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2DD8.ali
atm file:	2DD8.atm
cof file:	2DD8.cof
hbd file:	2DD8.hbd
html file:	2DD8.html
pdb file:	2DD8.pdb
ps file:	2DD8.ps
psa file:	2DD8.psa
rtf file:	2DD8.rtf
sst file:	2DD8.sst
tem file:	2DD8.tem