Pfam Domains mapped on to the structure: 2CN5

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00069	Protein kinase domain	PF00069	PF00069

Conserved Domain Database Superfamily Annotations: 2CN5

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2CN5	212301	cl09925	PKc_like	superfamily - -
2	2CN5	212301	cl09925	PKc_like	superfamily - -

Structural Details of PDB entry 2CN5 PDBid Chains Hinge Swapped Domain 2CN5 A,B A:375-378,B:375-378;A:402-407,B:402-407 A:379-401,B:379-401 Swapped-domain interface residues and interactions: Chains Residues A 379, 382, 383, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 408, 411, 412, 415, 427, 440, 441, 469, B 379, 382, 383, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 408, 411, 412, 415, 427, 440, 441, 469, Non-swapped-domain interface residues and interactions: Chains Residues A 346, 349, 350, 371, 373, 419, 425, 436, 437, 471, 474, 504, B 346, 349, 350, 371, 373, 419, 425, 436, 437, 471, 474,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2CN5

B:2CN5

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2CN5.ali
atm file:	2CN5.atm
cof file:	2CN5.cof
hbd file:	2CN5.hbd
html file:	2CN5.html
pdb file:	2CN5.pdb
ps file:	2CN5.ps
psa file:	2CN5.psa
rtf file:	2CN5.rtf
sst file:	2CN5.sst
tem file:	2CN5.tem