Pfam Domains mapped on to the structure: 2CN4

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF06438	Heme-binding protein A (HasA)	PF06438	PF06438

Conserved Domain Database Superfamily Annotations: 2CN4

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2CN4	203450	cl05770	HasA	superfamily - -

Structural Details of PDB entry 2CN4 PDBid Chains Hinge Swapped Domain 2CN4 A,B A:48-50,B:48-50 A:2-47,B:2-47 Swapped-domain interface residues and interactions: Chains Residues A 2, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 15, 16, 17, 19, 20, 23, 24, 26, 27, 28, 29, 30, 32, 33, 34, 39, 40, 41, 42, 43, 44, 45, 46, 47, 51, 52, 53, 54, 55, 56, 57, 59, 60, 61, 65, 101, 102, 105, 112, 113, 114, 115, 116, 117, 140, 141, 142, 144, 162, 163, 164, 165, 166, 167, 170, 173, B 2, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 15, 16, 17, 19, 20, 23, 24, 26, 27, 28, 29, 30, 32, 33, 34, 39, 40, 41, 42, 43, 44, 45, 46, 47, 51, 52, 53, 54, 55, 56, 57, 59, 60, 61, 65, 66, 101, 102, 105, 106, 112, 113, 114, 115, 116, 117, 140, 141, 142, 144, 162, 163, 164, 165, 166, 167, 170, 173, Non-swapped-domain interface residues and interactions: Chains Residues A 48, 49, 50, 62, 66, 67, 75, 78, 83, 94, 103, 104, 106, 111, 137, 139, 147, 148, 151, 154, 155, 158, 169, 174, B 48, 49, 50, 58, 62, 67, 75, 78, 94, 103, 104, 111, 137, 139, 147, 148, 151, 154, 155, 158, 169,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2CN4

B:2CN4

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2CN4.ali
atm file:	2CN4.atm
cof file:	2CN4.cof
hbd file:	2CN4.hbd
html file:	2CN4.html
pdb file:	2CN4.pdb
ps file:	2CN4.ps
psa file:	2CN4.psa
rtf file:	2CN4.rtf
sst file:	2CN4.sst
tem file:	2CN4.tem