Pfam Domains mapped on to the structure: 2CG4

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF08279	HTH domain	PF08279	PF08279
2	A	PF01037	AsnC family	PF01037	PF01037

Conserved Domain Database Superfamily Annotations: 2CG4

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2CG4	189815	cl16958	AsnC_trans_reg	superfamily - -
2	2CG4	212173	cl00088	HTH	superfamily - -
3	2CG4	212173	cl00088	HTH	superfamily - -

Structural Details of PDB entry 2CG4 PDBid Chains Hinge Swapped Domain 2CG4 A,B A:60-64,B:60-64 A:4-59,B:4-59 Swapped-domain interface residues and interactions: Chains Residues A 6, 14, 17, 18, 19, 20, 21, 22, 25, 47, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 63, 64, B 6, 14, 17, 18, 19, 20, 21, 22, 47, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 63, 64, Non-swapped-domain interface residues and interactions: Chains Residues A 61, 66, 71, 82, 86, 90, 93, 95, 96, 97, 98, 99, 100, 101, 102, 103, 105, 108, 110, 112, 114, 137, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, B 61, 66, 71, 82, 86, 90, 93, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 108, 110, 112, 114, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	GLU(37)GLY,
B	No mutation	No mutation	No mutation	GLU(37)GLY,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2CG4

B:2CG4

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2CG4.ali
atm file:	2CG4.atm
cof file:	2CG4.cof
hbd file:	2CG4.hbd
pdb file:	2CG4.pdb
psa file:	2CG4.psa
sst file:	2CG4.sst