Pfam Domains mapped on to the structure: 2CAG
Conserved Domain Database Superfamily Annotations: 2CAG
Structural Details of PDB entry 2CAG
Structural Details of PDB entry 2CAG
PDBid
Chains
Hinge
Swapped Domain
2CAG
A,C
A:356-373,C:356-373
A:374-478,C:374-478
Swapped-domain interface residues and interactions:
Chains
Residues
A
4 , 5 , 6 , 13 , 14 , 15 , 16 , 17 , 302 , 303 , 306 , 374 , 375 , 377 , 378 , 383 , 384 , 388 , 389 , 390 , 391 , 392 , 393 , 394 , 396 , 397 , 401 , 403 , 407 , 478 ,
C
4 , 5 , 6 , 13 , 14 , 15 , 16 , 17 , 302 , 303 , 306 , 374 , 375 , 377 , 378 , 383 , 384 , 388 , 389 , 390 , 391 , 392 , 393 , 394 , 396 , 397 , 401 , 403 , 407 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
7 , 8 , 9 , 10 , 11 , 12 , 18 , 23 , 28 , 30 , 31 , 32 , 34 , 35 , 37 , 38 , 39 , 41 , 42 , 45 , 46 , 48 , 119 , 120 , 121 , 305 , 310 , 316 , 317 , 318 , 320 , 324 , 331 , 332 , 334 , 335 , 339 , 342 , 345 , 347 , 348 , 350 , 351 , 352 , 353 , 357 , 360 , 361 , 362 , 363 , 364 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 ,
C
7 , 8 , 9 , 10 , 11 , 12 , 18 , 23 , 28 , 30 , 31 , 32 , 34 , 35 , 37 , 38 , 39 , 41 , 42 , 45 , 46 , 48 , 119 , 120 , 121 , 305 , 310 , 316 , 317 , 318 , 320 , 324 , 331 , 332 , 334 , 335 , 339 , 342 , 345 , 347 , 348 , 350 , 351 , 352 , 353 , 357 , 360 , 361 , 362 , 363 , 364 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
C No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: