Pfam Domains mapped on to the structure: 2C3B

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00160	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	PF00160	PF00160

Conserved Domain Database Superfamily Annotations: 2C3B

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2C3B	206894	cl00197	cyclophilin	superfamily - -

Structural Details of PDB entry 2C3B PDBid Chains Hinge Swapped Domain 2C3B A,B A:68-92,B:68-92;A:124-129,B:124-129 A:93-123,B:93-123 Swapped-domain interface residues and interactions: Chains Residues A 62, 63, 64, 65, 66, 67, 68, 69, 95, 97, 98, 99, 100, 101, 102, 103, 104, 114, 115, 116, 117, 118, 119, 120, 122, 128, 129, 130, 131, 132, 133, 134, 135, 141, B 62, 63, 64, 65, 66, 67, 68, 97, 98, 99, 100, 101, 102, 103, 104, 113, 114, 115, 116, 117, 118, 119, 120, 121, 128, 129, 130, 131, 132, 133, 134, 135, 141, Non-swapped-domain interface residues and interactions: Chains Residues A 6, 25, 35, 38, 39, 42, 51, 61, 124, 125, 127, 138, 144, 145, 148, 153, 171, B 6, 25, 28, 35, 38, 39, 51, 60, 61, 124, 125, 126, 127, 144, 148, 153,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2C3B

B:2C3B

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2C3B.ali
atm file:	2C3B.atm
cof file:	2C3B.cof
hbd file:	2C3B.hbd
html file:	2C3B.html
pdb file:	2C3B.pdb
ps file:	2C3B.ps
psa file:	2C3B.psa
rtf file:	2C3B.rtf
sst file:	2C3B.sst
tem file:	2C3B.tem