3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2BH8

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF08206 Ribonuclease B OB domain PF08206 PF08206

2 A PF00575 S1 RNA binding domain PF00575 PF00575

Gene Ontology Annotations: 2BH8

No. GO ID GO Description Linkout - AmiGO

1 GO:0003723 RNA binding GO:0003723

Conserved Domain Database Superfamily Annotations: 2BH8

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2BH8 88424 CSP_CDS C cl09927

2 2BH8 209094 S1_like superfamily C -

3 2BH8 209094 S1_like superfamily C -

Structural Details of PDB entry 2BH8

Structural Details of PDB entry 2BH8

PDBid Chains Hinge Swapped Domain

2BH8 A,D,C,B A:72-76,D:72-75,C:72-75,B:72-76 A:77-102,D:76-102,C:76-102,B:77-101

Swapped-domain interface residues and interactions:

Chains Residues
A 42, 43, 44, 45, 46, 47, 48, 58, 59, 61, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 77, 78, 79, 80, 81, 82, 83, 88, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102,

B 42, 43, 44, 45, 46, 47, 48, 52, 53, 58, 59, 60, 61, 62, 66, 67, 68, 69, 70, 71, 72, 73, 74, 77, 78, 79, 80, 81, 82, 83, 88, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 19, 26, 28, 34, 41, 49, 75, 76,

B 19, 26, 28, 41, 49, 51, 65, 75, 76,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

D No mutation No mutation No mutation No mutation

C No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2BH8 B:2BH8 C:2BH8 D:2BH8

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2BH8.ali
atm file: 2BH8.atm
cof file: 2BH8.cof
hbd file: 2BH8.hbd
html file: 2BH8.html
pdb file: 2BH8.pdb
ps file: 2BH8.ps
psa file: 2BH8.psa
rtf file: 2BH8.rtf
sst file: 2BH8.sst
tem file: 2BH8.tem