Pfam Domains mapped on to the structure: 2AVD

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01596	O-methyltransferase	PF01596	PF01596
2	A	PF12847	Methyltransferase domain	PF12847	PF12847
3	A	PF13578	Methyltransferase domain	PF13578	PF13578

Conserved Domain Database Superfamily Annotations: 2AVD

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2AVD	100107	cd02440	AdoMet_MTases -	cl16911
2	2AVD	212630	cl16911	AdoMet_MTases	superfamily - -
3	2AVD	212630	cl16911	AdoMet_MTases	superfamily - -

Structural Details of PDB entry 2AVD PDBid Chains Hinge Swapped Domain 2AVD A,B A:63-66,B:63-66 A:44-62,B:44-62 Swapped-domain interface residues and interactions: Chains Residues A 44, 45, 46, 47, 48, 53, 54, 55, 57, 58, 60, 61, 62, 217, 236, 237, 240, 247, 248, 249, B 44, 46, 47, 48, 53, 54, 57, 58, 60, 61, 62, 217, 236, 237, 240, 247, 248, 249, Non-swapped-domain interface residues and interactions: Chains Residues A 64, 92, 93, 96, 97, 99, 100, 101, 205, 214, 219, 220, 221, 245, 246, 250, 251, 252, 260, 262, B 64, 92, 93, 96, 97, 99, 100, 101, 205, 214, 219, 220, 221, 245, 246, 250, 251, 252, 260,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:2AVD

A:2AVD

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2AVD.ali
atm file:	2AVD.atm
cof file:	2AVD.cof
hbd file:	2AVD.hbd
html file:	2AVD.html
pdb file:	2AVD.pdb
ps file:	2AVD.ps
psa file:	2AVD.psa
rtf file:	2AVD.rtf
sst file:	2AVD.sst
tem file:	2AVD.tem