3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2ATR

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13527 Acetyltransferase (GNAT) domain PF13527 PF13527

2 A PF13673 Acetyltransferase (GNAT) domain PF13673 PF13673

3 A PF13508 Acetyltransferase (GNAT) domain PF13508 PF13508

4 A PF00583 Acetyltransferase (GNAT) family PF00583 PF00583

Conserved Domain Database Superfamily Annotations: 2ATR

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2ATR 173926 cd04301 NAT_SF - cl00357

2 2ATR 212199 cl00357 NAT_SF superfamily - -

3 2ATR 212199 cl00357 NAT_SF superfamily - -

Structural Details of PDB entry 2ATR

Structural Details of PDB entry 2ATR

PDBid Chains Hinge Swapped Domain

2ATR A,B A:129-130,B:129-130 A:131-137,B:131-137

Swapped-domain interface residues and interactions:

Chains Residues
A 96, 101, 102, 103, 119, 120, 121, 122, 123, 132, 133, 134, 135, 136, 137,

B 96, 101, 102, 103, 119, 120, 121, 122, 123, 132, 133, 134, 135, 136,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 25, 26, 34, 36, 37, 40, 58, 60, 61, 62, 64, 65, 66, 68, 70, 92, 98, 99, 100, 104, 105, 106, 107, 124, 126, 127, 128, 129, 130,

B 25, 26, 34, 36, 37, 40, 58, 60, 61, 62, 64, 65, 66, 68, 70, 92, 98, 99, 100, 104, 105, 106, 107, 124, 126, 127, 128, 129, 130,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2ATR B:2ATR

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2ATR.ali
atm file: 2ATR.atm
cof file: 2ATR.cof
hbd file: 2ATR.hbd
html file: 2ATR.html
pdb file: 2ATR.pdb
ps file: 2ATR.ps
psa file: 2ATR.psa
rtf file: 2ATR.rtf
sst file: 2ATR.sst
tem file: 2ATR.tem