Pfam Domains mapped on to the structure: 2ASK

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00019	Transforming growth factor beta like domain	PF00019	PF00019

Conserved Domain Database Superfamily Annotations: 2ASK

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2ASK	207620	cl02510	TGF_beta	superfamily - -

Structural Details of PDB entry 2ASK PDBid Chains Hinge Swapped Domain 2ASK A,B A:48-51,B:48-51;A:78-81,B:78-81 A:52-77,B:52-77 Swapped-domain interface residues and interactions: Chains Residues A 13, 14, 27, 28, 29, 43, 44, 45, 52, 53, 54, 55, 57, 58, 60, 61, 64, 66, 67, 68, 70, 71, 72, 73, 75, 76, 104, B 13, 14, 23, 27, 28, 29, 43, 44, 45, 46, 52, 53, 54, 55, 57, 58, 60, 61, 64, 66, 67, 68, 70, 71, 72, 73, 75, 76, 103, 104, Non-swapped-domain interface residues and interactions: Chains Residues A 19, 20, 21, 23, 40, 42, 80, 81, 82, 83, 86, 101, 112, 113, B 19, 21, 24, 40, 42, 80, 81, 82, 83, 86, 101, 112,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2ASK

B:2ASK

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2ASK.ali
atm file:	2ASK.atm
cof file:	2ASK.cof
hbd file:	2ASK.hbd
html file:	2ASK.html
pdb file:	2ASK.pdb
ps file:	2ASK.ps
psa file:	2ASK.psa
rtf file:	2ASK.rtf
sst file:	2ASK.sst
tem file:	2ASK.tem