Pfam Domains mapped on to the structure: 2AQX

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03770	Inositol polyphosphate kinase	PF03770	PF03770

Gene Ontology Annotations: 2AQX

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	GO:0008440

Conserved Domain Database Superfamily Annotations: 2AQX

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2AQX	209486	cl12283	IPK	superfamily - -

Structural Details of PDB entry 2AQX PDBid Chains Hinge Swapped Domain 2AQX A,B A:660-662,B:660-662 A:650-659,B:651-659 Swapped-domain interface residues and interactions: Chains Residues A 650, 652, 653, 654, 655, 656, 657, 658, 659, 661, 662, 663, 664, 665, 666, 667, 668, 678, 819, B 652, 653, 654, 655, 656, 657, 658, 659, 661, 662, 663, 664, 665, 666, 667, 668, 678, 819, Non-swapped-domain interface residues and interactions: Chains Residues A 660, 676, 679, 681, 682, 684, 730, 731, 813, 817, 821, 884, 938, B 660, 676, 679, 681, 682, 684, 813, 817, 821, 884,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2AQX

B:2AQX

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2AQX.ali
atm file:	2AQX.atm
cof file:	2AQX.cof
hbd file:	2AQX.hbd
html file:	2AQX.html
pdb file:	2AQX.pdb
ps file:	2AQX.ps
psa file:	2AQX.psa
rtf file:	2AQX.rtf
sst file:	2AQX.sst
tem file:	2AQX.tem