Pfam Domains mapped on to the structure: 2AOA

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00017	SH2 domain	PF00017	PF00017

Conserved Domain Database Superfamily Annotations: 2AOA

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2AOA	199828	cd09941	SH2_Grb2_like -	cl15255
2	2AOA	210054	cl15255	SH2	superfamily - -

Structural Details of PDB entry 2AOA PDBid Chains Hinge Swapped Domain 2AOA A,B A:119-127,B:119-127 A:128-150,B:128-150 Swapped-domain interface residues and interactions: Chains Residues A 81, 82, 83, 118, 119, 120, 128, 131, 132, 134, 135, 137, 138, 140, 141, 142, 144, 145, 146, 147, 148, 149, 150, B 81, 82, 83, 128, 129, 131, 132, 135, 136, 137, 138, 139, 140, 141, 142, 144, 145, 146, 147, 148, Non-swapped-domain interface residues and interactions: Chains Residues A 58, 60, 80, 85, 95, 97, 99, 101, 106, 108, 110, 113, 117, 121, 122, 123, 124, 125, 126, 127, B 77, 85, 95, 97, 99, 101, 106, 108, 110, 113, 117, 118, 119, 120, 121, 123, 124, 125, 126, 127,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2AOA

B:2AOA

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2AOA.ali
atm file:	2AOA.atm
cof file:	2AOA.cof
hbd file:	2AOA.hbd
html file:	2AOA.html
pdb file:	2AOA.pdb
ps file:	2AOA.ps
psa file:	2AOA.psa
rtf file:	2AOA.rtf
sst file:	2AOA.sst
tem file:	2AOA.tem