Pfam Domains mapped on to the structure: 2A62 No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD 1 A PF00028 Cadherin domain PF00028 PF00028 2 A PF00028 Cadherin domain PF00028 PF00028 3 A PF00028 Cadherin domain PF00028 PF00028 Conserved Domain Database Superfamily Annotations: 2A62 No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD 1 2A62 206637 cd11304 Cadherin_repeat - cl15786 2 2A62 211469 cl15786 CA_like superfamily - - 3 2A62 206637 cd11304 Cadherin_repeat - cl15786 4 2A62 211469 cl15786 CA_like superfamily - - 5 2A62 206637 cd11304 Cadherin_repeat - cl15786 6 2A62 211469 cl15786 CA_like superfamily - - Structural Details of PDB entry 2A62 Structural Details of PDB entry 2A62 PDBid Chains Hinge Swapped Domain 2A62 A,B A:-,B:- A:1--1,B:1--1 Swapped-domain interface residues and interactions: Chains Residues Non-swapped-domain interface residues and interactions: Chains Residues A 1, 2, 3, 4, 5, 6, 7, 8, 10, 19, 20, 21, 22, 23, 24, 25, 26, 27, 54, 56, 75, 87, 90, 95, 138, 322, B 1, 2, 3, 4, 5, 6, 7, 8, 10, 19, 20, 21, 22, 23, 24, 25, 26, 27, 54, 56, 75, 87, 90, 95, 138, Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color. Mutations in critical regions: Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain HIDE output: Homologues found through HIDE algorithm JMOL Visualization: 2D-plot: A:2A62 B:2A62 JOY Structural annotation for hinge hinge and swapped domain: Hinge Swapped domain JOY output: ali file:2A62.ali atm file:2A62.atm cof file:2A62.cof hbd file:2A62.hbd html file:2A62.html pdb file:2A62.pdb ps file:2A62.ps psa file:2A62.psa rtf file:2A62.rtf sst file:2A62.sst tem file:2A62.tem