Pfam Domains mapped on to the structure: 2A4E

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00028	Cadherin domain	PF00028	PF00028
2	A	PF00028	Cadherin domain	PF00028	PF00028

Conserved Domain Database Superfamily Annotations: 2A4E

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2A4E	206637	cd11304	Cadherin_repeat -	cl15786
2	2A4E	211469	cl15786	CA_like	superfamily - -
3	2A4E	206637	cd11304	Cadherin_repeat -	cl15786
4	2A4E	211469	cl15786	CA_like	superfamily - -

Structural Details of PDB entry 2A4E PDBid Chains Hinge Swapped Domain 2A4E A,B A:-,B:- A:0-10,B:0-10 Swapped-domain interface residues and interactions: Chains Residues A 0, 1, 2, 3, 4, 5, 6, 7, 8, 10, 19, 22, 25, 27, 87, B 0, 1, 2, 3, 4, 5, 6, 7, 8, 10, 19, 22, 25, 27, 87, Non-swapped-domain interface residues and interactions: Chains Residues A 13, 17, 18, 20, 23, 24, 56, 58, 75, 88, 90, 95, 97, 99, 100, 138, 207, B 13, 17, 18, 20, 23, 24, 56, 58, 75, 88, 90, 95, 97, 99, 100, 138,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2A4E

B:2A4E

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2A4E.ali
atm file:	2A4E.atm
cof file:	2A4E.cof
hbd file:	2A4E.hbd
html file:	2A4E.html
pdb file:	2A4E.pdb
ps file:	2A4E.ps
psa file:	2A4E.psa
rtf file:	2A4E.rtf
sst file:	2A4E.sst
tem file:	2A4E.tem