Pfam Domains mapped on to the structure: 2A4C No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD 1 A PF00028 Cadherin domain PF00028 PF00028 Conserved Domain Database Superfamily Annotations: 2A4C No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD 1 2A4C 206637 cd11304 Cadherin_repeat - cl15786 2 2A4C 211469 cl15786 CA_like superfamily - - Structural Details of PDB entry 2A4C Structural Details of PDB entry 2A4C PDBid Chains Hinge Swapped Domain 2A4C A,B A:-,B:- A:0--1,B:0--1 Swapped-domain interface residues and interactions: Chains Residues A 0, 87, B 0, 87, Non-swapped-domain interface residues and interactions: Chains Residues A 1, 2, 3, 4, 5, 6, 7, 8, 10, 13, 19, 20, 21, 22, 23, 24, 25, 26, 27, 75, 88, 90, 97, 98, B 1, 2, 3, 4, 5, 6, 7, 8, 10, 13, 19, 20, 21, 22, 23, 24, 25, 26, 27, 75, 77, 88, 90, 95, 97, Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color. Mutations in critical regions: Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain HIDE output: Homologues found through HIDE algorithm JMOL Visualization: 2D-plot: A:2A4C B:2A4C JOY Structural annotation for hinge hinge and swapped domain: Hinge Swapped domain JOY output: ali file:2A4C.ali atm file:2A4C.atm cof file:2A4C.cof hbd file:2A4C.hbd html file:2A4C.html pdb file:2A4C.pdb ps file:2A4C.ps psa file:2A4C.psa rtf file:2A4C.rtf sst file:2A4C.sst tem file:2A4C.tem