3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1YQV

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 L PF13895 Immunoglobulin domain PF13895 PF13895

2 L PF13927 Immunoglobulin domain PF13927 PF13927

3 L PF00047 Immunoglobulin domain PF00047 PF00047

4 H PF13895 Immunoglobulin domain PF13895 PF13895

5 Y PF00062 C-type lysozyme/alpha-lactalbumin family PF00062 PF00062

6 Y PF01464 Transglycosylase SLT domain PF01464 PF01464

Conserved Domain Database Superfamily Annotations: 1YQV

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1YQV 29018 cd00119 LYZ1 - cl00222

2 1YQV 212597 cl00222 lysozyme_like superfamily - -

Structural Details of PDB entry 1YQV

Structural Details of PDB entry 1YQV

PDBid Chains Hinge Swapped Domain

1YQV H,L H:42-46,L:41-45 H:1-41,L:0-40

Swapped-domain interface residues and interactions:

Chains Residues
H 35, 37, 39,

L 0, 1, 36, 38,

Non-swapped-domain interface residues and interactions:

Chains Residues
H 44, 45, 47, 60, 61, 91, 95, 96, 97, 101, 103, 104, 105, 122, 123, 124, 125, 126, 127, 133, 139, 143, 145, 167, 168, 172, 173, 174, 175, 177, 179, 186, 188, 190, 221,

L 43, 44, 46, 49, 50, 55, 56, 87, 91, 94, 95, 97, 98, 100, 116, 117, 118, 119, 121, 123, 124, 127, 131, 133, 135, 137, 138, 160, 161, 162, 163, 164, 167, 169, 174, 176, 178, 180, 207, 212,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

H No mutation No mutation No mutation No mutation

L No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:1YQV

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1YQV.ali
atm file: 1YQV.atm
cof file: 1YQV.cof
hbd file: 1YQV.hbd
html file: 1YQV.html
pdb file: 1YQV.pdb
ps file: 1YQV.ps
psa file: 1YQV.psa
rtf file: 1YQV.rtf
sst file: 1YQV.sst
tem file: 1YQV.tem