3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1Y9W

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13420 Acetyltransferase (GNAT) domain PF13420 PF13420

2 A PF13673 Acetyltransferase (GNAT) domain PF13673 PF13673

3 A PF13508 Acetyltransferase (GNAT) domain PF13508 PF13508

4 A PF00583 Acetyltransferase (GNAT) family PF00583 PF00583

Conserved Domain Database Superfamily Annotations: 1Y9W

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1Y9W 173926 cd04301 NAT_SF - cl00357

2 1Y9W 212199 cl00357 NAT_SF superfamily - -

Structural Details of PDB entry 1Y9W

Structural Details of PDB entry 1Y9W

PDBid Chains Hinge Swapped Domain

1Y9W A,B A:30-36,B:30-36 A:1-29,B:1-29

Swapped-domain interface residues and interactions:

Chains Residues
A 3, 4, 5, 6, 7, 8, 9, 11, 13, 14, 16, 17, 18, 20, 21, 24, 25, 28, 29, 41, 42, 43, 44, 45, 46, 54, 56, 68, 70,

B 1, 3, 4, 5, 6, 7, 8, 9, 13, 14, 16, 17, 18, 20, 21, 24, 25, 28, 29, 41, 42, 43, 44, 45, 46, 47, 54, 56, 68, 70,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 32, 33, 47, 51, 52, 61, 63, 69, 80, 83, 87, 98, 99, 101, 105, 107, 108, 121, 122, 123, 124, 125, 126, 127, 128, 129, 131, 135, 139, 140,

B 32, 33, 39, 51, 52, 61, 63, 69, 73, 75, 76, 80, 83, 84, 87, 91, 98, 99, 101, 105, 107, 108, 121, 122, 123, 124, 125, 126, 127, 128, 129, 131, 135, 137, 139,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1Y9W B:1Y9W

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1Y9W.ali
atm file: 1Y9W.atm
cof file: 1Y9W.cof
hbd file: 1Y9W.hbd
html file: 1Y9W.html
pdb file: 1Y9W.pdb
ps file: 1Y9W.ps
psa file: 1Y9W.psa
rtf file: 1Y9W.rtf
sst file: 1Y9W.sst
tem file: 1Y9W.tem