Pfam Domains mapped on to the structure: 1Y94

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00074	Pancreatic ribonuclease	PF00074	PF00074

Conserved Domain Database Superfamily Annotations: 1Y94

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1Y94	119387	cd06265	RNase_A_canonical -	cl00128
2	1Y94	206850	cl00128	RNase_A	superfamily - -

Structural Details of PDB entry 1Y94 PDBid Chains Hinge Swapped Domain 1Y94 A,B A:16-22,B:16-22 A:1-15,B:1-15 Swapped-domain interface residues and interactions: Chains Residues A 4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 33, 45, 46, 47, 48, 49, 50, 51, 116, 117, 118, 119, B 4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 33, 45, 46, 47, 48, 49, 50, 51, 116, 117, 118, Non-swapped-domain interface residues and interactions: Chains Residues A 16, 17, 19, 20, 22, 25, 28, 29, 31, 32, 34, 35, 41, 44, 54, 101, 120, 124, B 19, 20, 22, 25, 28, 29, 31, 32, 34, 35, 37, 41, 44, 54, 80, 101, 120,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	SER(16)GLY, THR(17)ASN, ALA(19)PRO, ALA(20)SER,	No mutation	SER(16)GLY, THR(17)ASN, ALA(19)PRO, ALA(20)SER,	No mutation
B	SER(16)GLY, THR(17)ASN, ALA(19)PRO, ALA(20)SER,	No mutation	ALA(19)PRO, ALA(20)SER,	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1Y94

B:1Y94

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1Y94.ali
atm file:	1Y94.atm
cof file:	1Y94.cof
hbd file:	1Y94.hbd
html file:	1Y94.html
pdb file:	1Y94.pdb
ps file:	1Y94.ps
psa file:	1Y94.psa
rtf file:	1Y94.rtf
sst file:	1Y94.sst
tem file:	1Y94.tem