3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1Y1X

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13405 EF-hand domain PF13405 PF13405

2 A PF13405 EF-hand domain PF13405 PF13405

3 A PF13405 EF-hand domain PF13405 PF13405

4 A PF13499 EF-hand domain pair PF13499 PF13499

5 A PF13499 EF-hand domain pair PF13499 PF13499

6 A PF13833 EF-hand domain pair PF13833 PF13833

7 A PF13833 EF-hand domain pair PF13833 PF13833

Conserved Domain Database Superfamily Annotations: 1Y1X

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1Y1X 28933 cd00051 EFh - cl08302

2 1Y1X 208857 cl08302 EFh superfamily - -

3 1Y1X 28933 cd00051 EFh - cl08302

4 1Y1X 208857 cl08302 EFh superfamily - -

5 1Y1X 208857 cl08302 EFh superfamily - -

6 1Y1X 208857 cl08302 EFh superfamily - -

Structural Details of PDB entry 1Y1X

Structural Details of PDB entry 1Y1X

PDBid Chains Hinge Swapped Domain

1Y1X A,B A:170-173,B:170-173 A:174-191,B:174-191

Swapped-domain interface residues and interactions:

Chains Residues
A 124, 125, 126, 127, 130, 134, 161, 174, 175, 176, 177, 178, 179, 180, 181, 183, 184, 185, 187, 188, 189, 190, 191,

B 125, 126, 127, 130, 134, 161, 165, 174, 175, 176, 177, 178, 179, 180, 181, 183, 184, 185, 187, 188, 189, 190,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 76, 133, 137, 138, 142, 157, 158, 164, 165,

B 76, 124, 133, 137, 138, 142, 157, 158,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1Y1X B:1Y1X

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1Y1X.ali
atm file: 1Y1X.atm
cof file: 1Y1X.cof
hbd file: 1Y1X.hbd
html file: 1Y1X.html
pdb file: 1Y1X.pdb
ps file: 1Y1X.ps
psa file: 1Y1X.psa
rtf file: 1Y1X.rtf
sst file: 1Y1X.sst
tem file: 1Y1X.tem