Pfam Domains mapped on to the structure: 1XKD
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00180
Isocitrate/isopropylmalate dehydrogenase
PF00180
PF00180
Conserved Domain Database Superfamily Annotations: 1XKD
Structural Details of PDB entry 1XKD
Structural Details of PDB entry 1XKD
PDBid Chains Hinge Swapped Domain
1XKD
A,B
A:168-170,B:168-170
A:171-300,B:171-300
Swapped-domain interface residues and interactions:
Chains Residues
A
145 , 146 , 147 , 148 , 149 , 163 , 165 , 166 , 168 , 169 , 170 , 171 , 172 , 173 , 177 , 180 , 181 , 184 , 185 , 188 , 189 , 191 , 193 , 194 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 242 , 245 , 246 , 247 , 285 , 286 , 287 , 290 , 291 , 294 , 295 , 296 , 308 , 309 , 311 , 312 , 315 , 316 , 319 , 320 , 324 , 435 ,
B
112 , 113 , 114 , 115 , 116 , 117 , 119 , 120 , 123 , 145 , 146 , 147 , 148 , 149 , 165 , 166 , 169 , 170 , 171 , 172 , 173 , 177 , 180 , 181 , 184 , 185 , 188 , 189 , 191 , 193 , 194 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 233 , 236 , 237 , 239 , 240 , 247 , 286 , 287 , 290 , 291 , 294 , 295 , 308 , 309 , 311 , 312 , 315 , 316 , 319 , 320 , 323 , 324 , 348 , 400 , 401 , 402 ,
Non-swapped-domain interface residues and interactions:
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
