Pfam Domains mapped on to the structure: 1XGV

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00180	Isocitrate/isopropylmalate dehydrogenase	PF00180	PF00180

Conserved Domain Database Superfamily Annotations: 1XGV

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1XGV	212218	cl00445	Iso_dh	superfamily - -
2	1XGV	212218	cl00445	Iso_dh	superfamily - -

Structural Details of PDB entry 1XGV PDBid Chains Hinge Swapped Domain 1XGV A,B A:196-197,B:196-197 A:198-300,B:198-300 Swapped-domain interface residues and interactions: Chains Residues A 118, 145, 146, 147, 148, 149, 163, 165, 166, 168, 169, 170, 171, 172, 173, 177, 180, 181, 184, 185, 188, 189, 191, 193, 194, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 233, 236, 237, 239, 240, 247, 286, 287, 290, 291, 294, 295, 308, 309, 311, 312, 315, 316, 319, 320, 324, 435, B 145, 146, 147, 148, 149, 163, 165, 166, 168, 169, 170, 171, 172, 173, 177, 180, 181, 184, 185, 188, 189, 191, 193, 194, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 233, 235, 236, 237, 239, 240, 247, 286, 287, 290, 291, 294, 295, 308, 309, 311, 312, 315, 316, 319, 320, 324, Non-swapped-domain interface residues and interactions: Chains Residues

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1XGV

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1XGV.ali
atm file:	1XGV.atm
cof file:	1XGV.cof
hbd file:	1XGV.hbd
html file:	1XGV.html
pdb file:	1XGV.pdb
ps file:	1XGV.ps
psa file:	1XGV.psa
rtf file:	1XGV.rtf
sst file:	1XGV.sst
tem file:	1XGV.tem