Pfam Domains mapped on to the structure: 1XG4

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13714	Phosphoenolpyruvate phosphomutase	PF13714	PF13714
2	A	PF00463	Isocitrate lyase family	PF00463	PF00463

Conserved Domain Database Superfamily Annotations: 1XG4

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1XG4	119340	cd00377	ICL_PEPM -	cl00435
2	1XG4	212216	cl00435	ICL_KPHMT	superfamily - -
3	1XG4	212216	cl00435	ICL_KPHMT	superfamily - -

Structural Details of PDB entry 1XG4 PDBid Chains Hinge Swapped Domain 1XG4 A,B A:46-58,B:46-58 A:2-45,B:3-45 Swapped-domain interface residues and interactions: Chains Residues A 17, 21, 23, 27, 28, 29, 30, 33, 34, 37, 38, 39, 51, 52, 53, 54, 55, 248, 251, 252, B 17, 21, 23, 27, 28, 29, 30, 33, 34, 37, 38, 39, 51, 52, 53, 54, 55, 248, 251, 252, Non-swapped-domain interface residues and interactions: Chains Residues A 56, 57, 58, 59, 61, 66, 69, 73, 77, 120, 122, 123, 125, 126, 128, 213, 214, 219, 221, 222, 235, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 250, 254, 255, 258, 259, 260, 261, 264, 265, 266, 267, 268, 269, 270, 272, 273, 274, 277, 279, 280, 282, 283, 286, 287, 288, B 56, 57, 58, 59, 61, 66, 69, 73, 77, 120, 122, 123, 125, 126, 128, 213, 214, 219, 221, 222, 235, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 250, 254, 255, 258, 259, 260, 261, 264, 265, 266, 267, 268, 269, 270, 272, 273, 274, 277, 279, 280, 282, 283, 286, 287,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	SER(123)CYS,	No mutation
B	No mutation	No mutation	SER(123)CYS,	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1XG4

B:1XG4

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1XG4.ali
atm file:	1XG4.atm
cof file:	1XG4.cof
hbd file:	1XG4.hbd
html file:	1XG4.html
pdb file:	1XG4.pdb
ps file:	1XG4.ps
psa file:	1XG4.psa
rtf file:	1XG4.rtf
sst file:	1XG4.sst
tem file:	1XG4.tem