3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1X9I

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF01380 SIS domain PF01380 PF01380

Conserved Domain Database Superfamily Annotations: 1X9I

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1X9I 88412 cd05017 SIS_PGI_PMI_1 - cl00389

2 1X9I 207026 cl00389 SIS superfamily - -

3 1X9I 88413 cd05637 SIS_PGI_PMI_2 - cl00389

4 1X9I 207026 cl00389 SIS superfamily - -

5 1X9I 207026 cl00389 SIS superfamily - -

Structural Details of PDB entry 1X9I

Structural Details of PDB entry 1X9I

PDBid Chains Hinge Swapped Domain

1X9I A,B A:286-289,B:286-289 A:290-301,B:290-301

Swapped-domain interface residues and interactions:

Chains Residues
A 218, 219, 222, 223, 293, 294, 297, 298, 300, 301,

B 218, 219, 222, 223, 293, 294, 297, 298, 300, 301,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 38, 39, 41, 45, 46, 59, 60, 63, 65, 67, 69, 72, 73, 74, 75, 77, 78, 79, 80, 94, 97, 181, 188, 195, 198, 199, 202, 203, 206, 207, 208, 210, 212, 215, 216, 220, 221, 224, 225, 226, 227, 238, 240, 241, 243, 244, 246, 247, 250, 251,

B 38, 39, 41, 45, 46, 60, 63, 64, 65, 66, 67, 69, 72, 73, 74, 75, 77, 79, 80, 94, 97, 105, 181, 188, 195, 198, 199, 202, 203, 206, 207, 208, 210, 212, 215, 216, 220, 221, 224, 225, 226, 227, 238, 240, 241, 243, 244, 247, 250, 251, 252,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1X9I B:1X9I

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1X9I.ali
atm file: 1X9I.atm
cof file: 1X9I.cof
hbd file: 1X9I.hbd
html file: 1X9I.html
pdb file: 1X9I.pdb
ps file: 1X9I.ps
psa file: 1X9I.psa
rtf file: 1X9I.rtf
sst file: 1X9I.sst
tem file: 1X9I.tem