3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1X7D

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF02423 Ornithine cyclodeaminase/mu-crystallin family PF02423 PF02423

Conserved Domain Database Superfamily Annotations: 1X7D

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1X7D 212616 NADB_Rossmann superfamily N -

2 1X7D 212616 NADB_Rossmann superfamily N -

Structural Details of PDB entry 1X7D

Structural Details of PDB entry 1X7D

PDBid Chains Hinge Swapped Domain

1X7D A,B A:320-334,B:320-334 A:335-341,B:335-340

Swapped-domain interface residues and interactions:

Chains Residues
A 11, 12, 14, 15, 336, 337, 338, 339, 340, 341,

B 8, 11, 12, 14, 15, 336, 337, 338, 339,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 4, 6, 7, 8, 9, 19, 41, 43, 46, 48, 50, 51, 52, 55, 57, 59, 61, 63, 66, 68, 70, 72, 74, 77, 78, 80, 81, 82, 83, 87, 88, 90, 92, 94, 95, 96, 97, 99, 102, 106, 107, 138, 139, 142, 143, 163, 166, 169, 173, 176, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334,

B 4, 6, 7, 9, 19, 41, 43, 46, 48, 50, 51, 52, 55, 57, 59, 61, 66, 68, 70, 72, 74, 77, 78, 80, 81, 82, 83, 87, 88, 90, 92, 94, 95, 96, 97, 99, 102, 104, 106, 107, 138, 139, 142, 143, 163, 166, 169, 173, 176, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1X7D B:1X7D

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1X7D.ali
atm file: 1X7D.atm
cof file: 1X7D.cof
hbd file: 1X7D.hbd
html file: 1X7D.html
pdb file: 1X7D.pdb
ps file: 1X7D.ps
psa file: 1X7D.psa
rtf file: 1X7D.rtf
sst file: 1X7D.sst
tem file: 1X7D.tem