Pfam Domains mapped on to the structure: 1X2I

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF12826	Helix-hairpin-helix motif	PF12826	PF12826
2	A	PF00633	Helix-hairpin-helix motif	PF00633	PF00633

Gene Ontology Annotations: 1X2I

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0003677	DNA binding	GO:0003677

Conserved Domain Database Superfamily Annotations: 1X2I

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1X2I	209897	cl14786	ENDO3c	superfamily - -
2	1X2I	209897	cl14786	ENDO3c	superfamily - -

Structural Details of PDB entry 1X2I PDBid Chains Hinge Swapped Domain 1X2I A,B A:42-27,B:42-27 A:61-69,B:61-69 Swapped-domain interface residues and interactions: Chains Residues A 5, 6, 28, 29, 32, 33, 34, 35, 61, 62, 63, 64, 65, 66, 67, 68, 69, B 5, 6, 9, 28, 29, 32, 33, 34, 35, 61, 62, 63, 64, 65, 66, 67, 68, Non-swapped-domain interface residues and interactions: Chains Residues A 8, 9, 10, 12, 15, 17, 25, 36, 38, 39, 60, B 8, 10, 11, 12, 15, 16, 17, 25, 38, 39, 60,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1X2I

B:1X2I

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1X2I.ali
atm file:	1X2I.atm
cof file:	1X2I.cof
hbd file:	1X2I.hbd
html file:	1X2I.html
pdb file:	1X2I.pdb
ps file:	1X2I.ps
psa file:	1X2I.psa
rtf file:	1X2I.rtf
sst file:	1X2I.sst
tem file:	1X2I.tem