Pfam Domains mapped on to the structure: 1X0L

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00180	Isocitrate/isopropylmalate dehydrogenase	PF00180	PF00180

Conserved Domain Database Superfamily Annotations: 1X0L

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1X0L	212218	cl00445	Iso_dh	superfamily - -
2	1X0L	212218	cl00445	Iso_dh	superfamily - -

Structural Details of PDB entry 1X0L PDBid Chains Hinge Swapped Domain 1X0L A,B A:133-136,B:133-136 A:2-132,B:2-132 Swapped-domain interface residues and interactions: Chains Residues A 129, 130, 131, 177, B 129, 130, 131, 177, Non-swapped-domain interface residues and interactions: Chains Residues A 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 171, 174, 175, 176, 178, 181, 203, 204, 207, 208, 211, 212, 225, 226, 228, 229, 232, 233, 236, 237, 239, 240, 241, 334, B 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 171, 175, 178, 181, 203, 204, 205, 207, 208, 211, 212, 225, 228, 229, 232, 233, 236, 237, 240, 241,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1X0L

B:1X0L

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1X0L.ali
atm file:	1X0L.atm
cof file:	1X0L.cof
hbd file:	1X0L.hbd
html file:	1X0L.html
pdb file:	1X0L.pdb
ps file:	1X0L.ps
psa file:	1X0L.psa
rtf file:	1X0L.rtf
sst file:	1X0L.sst
tem file:	1X0L.tem