Pfam Domains mapped on to the structure: 1WWW

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	V	PF00243	Nerve growth factor family	PF00243	PF00243

Conserved Domain Database Superfamily Annotations: 1WWW

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1WWW	143172	cd04971	Ig_TrKABC_d5 -	cl11960
2	1WWW	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 1WWW PDBid Chains Hinge Swapped Domain 1WWW W,V W:13-16,V:13-16 W:2-12,V:2-12 Swapped-domain interface residues and interactions: Chains Residues V 8, 9, 10, 11, 12, 111, 112, 113, W 8, 10, 11, 12, 111, 112, 113, 114, Non-swapped-domain interface residues and interactions: Chains Residues V 13, 14, 21, 31, 42, 43, 44, 45, 49, 52, 54, 69, 70, 71, 72, 76, 79, 85, 86, 87, 88, 90, 99, 101, 106, 107, 108, 109, 110, 114, 115, W 14, 21, 31, 42, 43, 44, 45, 49, 52, 54, 69, 70, 71, 72, 76, 79, 85, 86, 87, 88, 90, 99, 101, 106, 107, 108, 109, 110,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
W	No mutation	No mutation	No mutation	No mutation
V	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1WWW

V:1WWW

W:1WWW

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1WWW.ali
atm file:	1WWW.atm
cof file:	1WWW.cof
hbd file:	1WWW.hbd
html file:	1WWW.html
pdb file:	1WWW.pdb
ps file:	1WWW.ps
psa file:	1WWW.psa
rtf file:	1WWW.rtf
sst file:	1WWW.sst
tem file:	1WWW.tem