Pfam Domains mapped on to the structure: 1WVQ
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF04008
Adenosine specific kinase
PF04008
PF04008
Conserved Domain Database Superfamily Annotations: 1WVQ
Structural Details of PDB entry 1WVQ
Structural Details of PDB entry 1WVQ
PDBid
Chains
Hinge
Swapped Domain
1WVQ
A,D,C,B
A:138-142,D:138-142,C:138-142,B:138-142
A:143-167,D:143-167,C:143-167,B:143-167
Swapped-domain interface residues and interactions:
Chains
Residues
A
53 , 55 , 59 , 60 , 61 , 62 , 79 , 82 , 143 , 144 , 145 , 146 , 147 , 151 , 152 , 154 , 155 , 158 , 159 , 160 , 165 , 166 , 167 ,
B
53 , 55 , 59 , 60 , 61 , 62 , 79 , 82 , 143 , 144 , 145 , 146 , 147 , 151 , 152 , 154 , 155 , 158 , 159 , 160 , 165 , 166 , 167 ,
C
53 , 55 , 59 , 60 , 61 , 62 , 79 , 82 , 84 , 143 , 144 , 145 , 146 , 147 , 151 , 152 , 154 , 155 , 158 , 159 , 160 , 165 , 166 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
6 , 8 , 10 , 25 , 26 , 27 , 28 , 29 , 30 , 32 , 33 , 34 , 37 , 56 , 58 , 63 , 64 , 75 , 84 , 96 , 97 , 100 , 101 , 104 , 105 , 107 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 118 , 119 , 121 , 123 , 125 , 127 , 128 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 ,
B
5 , 8 , 10 , 25 , 26 , 27 , 28 , 29 , 30 , 32 , 33 , 34 , 37 , 56 , 58 , 63 , 64 , 75 , 84 , 96 , 97 , 100 , 101 , 104 , 105 , 107 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 118 , 119 , 121 , 123 , 125 , 127 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 ,
C
6 , 8 , 10 , 25 , 26 , 27 , 28 , 29 , 30 , 32 , 33 , 34 , 37 , 56 , 58 , 63 , 64 , 75 , 96 , 97 , 100 , 101 , 104 , 105 , 107 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 118 , 119 , 121 , 123 , 125 , 127 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
D No mutation No mutation No mutation No mutation
C No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: