3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1WU7

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF03129 Anticodon binding domain PF03129 PF03129

Conserved Domain Database Superfamily Annotations: 1WU7

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1WU7 73226 cd00773 HisRS-like_core - cl00268

2 1WU7 206944 cl00268 class_II_aaRS-like_core superfamily - -

3 1WU7 29799 cd00859 HisRS_anticodon - cl00266

4 1WU7 206943 cl00266 HGTP_anticodon superfamily - -

5 1WU7 206943 cl00266 HGTP_anticodon superfamily - -

Structural Details of PDB entry 1WU7

Structural Details of PDB entry 1WU7

PDBid Chains Hinge Swapped Domain

1WU7 A,B A:326-334,B:326-334 A:335-426,B:335-424

Swapped-domain interface residues and interactions:

Chains Residues
A 35, 36, 37, 38, 136, 248, 251, 252, 345, 346, 349, 350, 353, 356, 361, 362, 363, 364, 366, 369, 373, 376, 377, 380, 381, 426,

B 35, 36, 37, 38, 97, 136, 137, 248, 251, 252, 345, 346, 349, 350, 353, 356, 361, 362, 363, 364, 366, 369, 377, 380, 381,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 3, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 17, 18, 21, 24, 27, 32, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 51, 52, 63, 66, 67, 68, 71, 76, 78, 88, 92, 93, 96, 97, 98, 99, 101, 102, 106, 107, 109, 111, 121, 123, 132, 134, 137, 140, 151, 253, 301, 332,

B 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17, 18, 21, 24, 27, 32, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 51, 52, 66, 68, 69, 70, 71, 72, 74, 76, 78, 88, 91, 92, 93, 96, 98, 99, 101, 102, 107, 109, 111, 121, 123, 132, 134, 140, 151, 253, 299, 301, 302, 332,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1WU7 B:1WU7

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1WU7.ali
atm file: 1WU7.atm
cof file: 1WU7.cof
hbd file: 1WU7.hbd
html file: 1WU7.html
pdb file: 1WU7.pdb
ps file: 1WU7.ps
psa file: 1WU7.psa
rtf file: 1WU7.rtf
sst file: 1WU7.sst
tem file: 1WU7.tem