Pfam Domains mapped on to the structure: 1WTJ
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF02615
Malate/L-lactate dehydrogenase
PF02615
PF02615
Conserved Domain Database Superfamily Annotations: 1WTJ
Structural Details of PDB entry 1WTJ
Structural Details of PDB entry 1WTJ
PDBid Chains Hinge Swapped Domain
1WTJ
A,B
A:288-285,B:288-285;A:309-311,B:309-311
A:286-308,B:286-308
Swapped-domain interface residues and interactions:
Chains Residues
A
82 , 156 , 157 , 158 , 159 , 160 , 161 , 247 , 251 , 252 , 254 , 286 , 287 , 289 , 291 , 294 , 295 , 297 , 298 , 301 , 302 , 304 , 305 , 306 , 307 ,
B
82 , 156 , 157 , 158 , 159 , 160 , 161 , 247 , 251 , 252 , 254 , 286 , 287 , 289 , 291 , 294 , 295 , 297 , 298 , 301 , 302 , 304 , 305 , 306 , 307 ,
Non-swapped-domain interface residues and interactions:
Chains Residues
A
83 , 84 , 85 , 86 , 88 , 114 , 115 , 116 , 118 , 143 , 145 , 163 , 164 , 169 , 171 , 181 , 183 , 185 , 186 , 189 , 233 , 234 , 236 , 237 , 240 , 241 , 243 , 244 , 248 , 255 , 257 , 259 , 260 , 279 , 281 , 283 , 285 , 311 , 341 ,
B
83 , 84 , 85 , 86 , 88 , 114 , 115 , 116 , 118 , 143 , 145 , 163 , 164 , 169 , 171 , 181 , 183 , 185 , 186 , 189 , 233 , 234 , 237 , 240 , 241 , 243 , 244 , 248 , 255 , 257 , 259 , 260 , 279 , 281 , 283 , 285 , 309 , 311 ,
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
