Pfam Domains mapped on to the structure: 1WNB
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00171
Aldehyde dehydrogenase family
PF00171
PF00171
Conserved Domain Database Superfamily Annotations: 1WNB
Structural Details of PDB entry 1WNB
Structural Details of PDB entry 1WNB
PDBid
Chains
Hinge
Swapped Domain
1WNB
A,B
A:116-119,B:116-119;A:136-141,B:136-141
A:120-135,B:120-135
Swapped-domain interface residues and interactions:
Chains
Residues
A
120 , 121 , 126 , 127 , 130 , 132 , 133 , 134 , 135 ,
C
439 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
52 , 57 , 136 , 139 , 218 , 226 , 230 , 233 , 234 , 237 , 238 , 239 , 240 , 242 , 247 , 419 , 422 , 423 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 434 , 437 , 439 , 441 , 442 , 443 , 446 , 447 , 448 , 449 , 452 , 454 , 458 , 459 , 466 , 467 , 468 , 469 , 470 , 471 , 472 , 473 , 474 ,
C
52 , 57 , 120 , 121 , 126 , 127 , 130 , 132 , 133 , 134 , 135 , 136 , 139 , 218 , 226 , 230 , 233 , 234 , 237 , 238 , 239 , 240 , 242 , 247 , 419 , 422 , 423 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 434 , 437 , 441 , 442 , 443 , 446 , 447 , 448 , 449 , 452 , 454 , 458 , 459 , 466 , 467 , 468 , 469 , 470 , 471 , 472 , 473 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: