Pfam Domains mapped on to the structure: 1WC3
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00211
Adenylate and Guanylate cyclase catalytic domain
PF00211
PF00211
Gene Ontology Annotations: 1WC3
Conserved Domain Database Superfamily Annotations: 1WC3
Structural Details of PDB entry 1WC3
Structural Details of PDB entry 1WC3
PDBid
Chains
Hinge
Swapped Domain
1WC3
A,B
A:1125-1126,B:1125-1126;A:1141-1142,B:1141-1142
A:1127-1140,B:1127-1140
Swapped-domain interface residues and interactions:
Chains
Residues
A
1034 , 1038 , 1041 , 1042 , 1045 , 1130 , 1131 , 1132 , 1134 , 1135 , 1137 ,
B
1038 , 1041 , 1042 , 1045 , 1130 , 1131 , 1132 , 1134 , 1135 , 1137 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
1006 , 1008 , 1019 , 1021 , 1022 , 1030 , 1031 , 1033 , 1037 , 1046 , 1049 , 1055 , 1056 , 1057 , 1058 , 1059 , 1060 , 1126 , 1141 , 1143 , 1146 ,
B
1005 , 1006 , 1008 , 1022 , 1026 , 1030 , 1031 , 1033 , 1034 , 1037 , 1046 , 1049 , 1055 , 1056 , 1057 , 1058 , 1059 , 1060 , 1126 , 1141 , 1143 , 1146 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: