Home BrowseSearch Help Group

Pfam Domains mapped on to the structure: 1WC3

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 A PF00211 Adenylate and Guanylate cyclase catalytic domain PF00211 PF00211

Gene Ontology Annotations: 1WC3

No. GO ID GO Description Linkout - AmiGO
1 GO:0035556 intracellular signal transduction GO:0035556

Conserved Domain Database Superfamily Annotations: 1WC3

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 1WC3 143636 cd07302 CHD - cl11967
2 1WC3 212337 cl11967 Nucleotidyl_cyc_III superfamily - -
Structural Details of PDB entry 1WC3

Structural Details of PDB entry 1WC3

PDBid Chains Hinge Swapped Domain
1WC3 A,B A:1125-1126,B:1125-1126;A:1141-1142,B:1141-1142 A:1127-1140,B:1127-1140

Swapped-domain interface residues and interactions:

Chains Residues
A 1034, 1038, 1041, 1042, 1045, 1130, 1131, 1132, 1134, 1135, 1137,
B 1038, 1041, 1042, 1045, 1130, 1131, 1132, 1134, 1135, 1137,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 1006, 1008, 1019, 1021, 1022, 1030, 1031, 1033, 1037, 1046, 1049, 1055, 1056, 1057, 1058, 1059, 1060, 1126, 1141, 1143, 1146,
B 1005, 1006, 1008, 1022, 1026, 1030, 1031, 1033, 1034, 1037, 1046, 1049, 1055, 1056, 1057, 1058, 1059, 1060, 1126, 1141, 1143, 1146,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
ANo mutationNo mutationNo mutationNo mutation
BNo mutationNo mutationNo mutationNo mutation
BNo mutationNo mutationNo mutationNo mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

B:1WC3 A:1WC3

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:1WC3.ali
atm file:1WC3.atm
cof file:1WC3.cof
hbd file:1WC3.hbd
html file:1WC3.html
pdb file:1WC3.pdb
ps file:1WC3.ps
psa file:1WC3.psa
rtf file:1WC3.rtf
sst file:1WC3.sst
tem file:1WC3.tem