3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1W1Z

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00490 Delta-aminolevulinic acid dehydratase PF00490 PF00490

Gene Ontology Annotations: 1W1Z

No. GO ID GO Description Linkout - AmiGO

1 GO:0033014 tetrapyrrole biosynthetic process GO:0033014

Conserved Domain Database Superfamily Annotations: 1W1Z

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1W1Z 88599 cd04823 ALAD_PBGS_aspartate_rich - cl00338

2 1W1Z 198575 cl00338 ALAD_PBGS superfamily - -

Structural Details of PDB entry 1W1Z

Structural Details of PDB entry 1W1Z

PDBid Chains Hinge Swapped Domain

1W1Z A,B A:28-35,B:28-35 A:10-27,B:10-27

Swapped-domain interface residues and interactions:

Chains Residues
A 11, 12, 13, 14, 16, 17, 18, 23, 27, 174, 223, 224, 225, 230, 231,

B 11, 12, 13, 14, 16, 17, 18, 23, 26, 27, 174, 223, 224, 225, 230, 231,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 28, 53, 54, 56, 143, 145, 146, 203, 204, 205, 207, 208, 228, 229, 232, 233, 234, 237, 238, 241, 256, 257, 258, 259, 260, 263, 264, 280, 283, 284, 285, 287, 288, 291, 293, 294, 298, 299, 302, 303, 305, 306, 309, 310, 328,

B 28, 53, 54, 56, 143, 145, 146, 203, 204, 205, 207, 208, 210, 228, 229, 232, 233, 234, 237, 238, 241, 256, 257, 258, 259, 260, 263, 264, 280, 283, 284, 285, 287, 288, 291, 293, 294, 298, 299, 302, 303, 305, 306, 309, 310,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1W1Z B:1W1Z

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1W1Z.ali
atm file: 1W1Z.atm
cof file: 1W1Z.cof
hbd file: 1W1Z.hbd
html file: 1W1Z.html
pdb file: 1W1Z.pdb
ps file: 1W1Z.ps
psa file: 1W1Z.psa
rtf file: 1W1Z.rtf
sst file: 1W1Z.sst
tem file: 1W1Z.tem