Pfam Domains mapped on to the structure: 1VPW

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00356	Bacterial regulatory proteins, lacI family	PF00356	PF00356
2	A	PF00532	Periplasmic binding proteins and sugar binding domain of LacI family	PF00532	PF00532
3	A	PF13407	Periplasmic binding protein domain	PF13407	PF13407
4	A	PF13377	Periplasmic binding protein-like domain	PF13377	PF13377

Gene Ontology Annotations: 1VPW

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005622	intracellular	GO:0005622

Conserved Domain Database Superfamily Annotations: 1VPW

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1VPW	107270	cd06275	PBP1_PurR -	cl10011
2	1VPW	209116	cl10011	Periplasmic_Binding_Protein_Type_1	superfamily - -
3	1VPW	143331	cd01392	HTH_LacI -	cl15761
4	1VPW	210161	cl15761	HTH_XRE	superfamily - -
5	1VPW	210161	cl15761	HTH_XRE	superfamily - -

Structural Details of PDB entry 1VPW PDBid Chains Hinge Swapped Domain 1VPW A,B A:57-60,B:57-60 A:3-56,B:3-56 Swapped-domain interface residues and interactions: Chains Residues A 3, 44, 46, 47, 48, 49, 50, 51, 53, 54, 112, 113, 114, B 3, 44, 46, 47, 48, 49, 50, 51, 53, 54, 112, 113, 114, Non-swapped-domain interface residues and interactions: Chains Residues A 59, 69, 70, 75, 76, 78, 79, 82, 83, 86, 89, 91, 92, 93, 94, 96, 98, 103, 106, 107, 110, 115, 136, 222, 223, 224, 227, 249, 252, 253, 256, 259, 260, 264, 278, 279, 281, 282, 284, 285, 329, 340, B 59, 69, 70, 75, 76, 78, 79, 82, 83, 86, 89, 91, 92, 93, 94, 96, 98, 103, 106, 107, 110, 115, 136, 222, 223, 224, 227, 249, 252, 253, 256, 259, 260, 264, 278, 279, 281, 282, 284, 285, 329,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1VPW

A:1VPW

B:1VPW

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1VPW.ali
atm file:	1VPW.atm
cof file:	1VPW.cof
hbd file:	1VPW.hbd
html file:	1VPW.html
pdb file:	1VPW.pdb
ps file:	1VPW.ps
psa file:	1VPW.psa
rtf file:	1VPW.rtf
sst file:	1VPW.sst
tem file:	1VPW.tem