Pfam Domains mapped on to the structure: 1VFR
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00881
Nitroreductase family
PF00881
PF00881
Conserved Domain Database Superfamily Annotations: 1VFR
Structural Details of PDB entry 1VFR
Structural Details of PDB entry 1VFR
PDBid
Chains
Hinge
Swapped Domain
1VFR
A,B
A:203-206,B:203-206
A:207-218,B:207-218
Swapped-domain interface residues and interactions:
Chains
Residues
A
37 , 38 , 48 , 49 , 50 , 51 , 52 , 54 , 100 , 103 , 104 , 107 , 109 , 207 , 208 , 209 , 210 , 211 , 213 , 214 , 215 , 216 , 217 , 218 ,
B
37 , 38 , 48 , 49 , 50 , 51 , 52 , 54 , 55 , 58 , 100 , 104 , 107 , 207 , 208 , 209 , 210 , 211 , 213 , 214 , 215 , 216 , 217 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
3 , 4 , 5 , 6 , 8 , 9 , 10 , 12 , 27 , 31 , 33 , 34 , 35 , 40 , 42 , 44 , 46 , 55 , 58 , 70 , 72 , 99 , 108 , 123 , 124 , 127 , 137 , 138 , 140 , 141 , 142 , 144 , 145 , 147 , 148 , 149 , 151 , 152 , 153 , 156 , 157 , 165 , 166 , 179 , 201 , 204 , 205 , 206 ,
B
3 , 4 , 5 , 6 , 8 , 9 , 10 , 12 , 27 , 31 , 33 , 34 , 35 , 40 , 42 , 44 , 46 , 70 , 72 , 99 , 103 , 108 , 109 , 124 , 127 , 137 , 138 , 140 , 141 , 142 , 144 , 145 , 147 , 148 , 149 , 151 , 152 , 153 , 156 , 157 , 165 , 166 , 179 , 201 , 204 , 205 , 206 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: