Pfam Domains mapped on to the structure: 1V8D

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF04260	Protein of unknown function (DUF436)	PF04260	PF04260

Conserved Domain Database Superfamily Annotations: 1V8D

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1V8D	186483	cl01860	DUF436	superfamily - -

Structural Details of PDB entry 1V8D PDBid Chains Hinge Swapped Domain 1V8D A,D,C,B A:207-210,D:207-210,C:207-210,B:207-210 A:211-232,D:211-232,C:211-232,B:211-232 Swapped-domain interface residues and interactions: Chains Residues A 114, 115, 116, 134, 135, 136, 137, 138, 139, 142, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 223, 226, 227, 229, 230, 231, 232, B 114, 115, 116, 134, 135, 136, 137, 138, 139, 142, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 223, 226, 227, 229, C 114, 115, 116, 134, 135, 136, 137, 138, 139, 142, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 223, 226, 227, Non-swapped-domain interface residues and interactions: Chains Residues A 83, 84, 86, 132, 133, 140, 141, 148, 151, 152, 157, 184, 208, 209, 210, B 83, 84, 86, 87, 132, 133, 140, 141, 148, 151, 152, 161, 183, 208, 209, 210, C 86, 132, 133, 140, 141, 148, 151, 152, 161, 184, 208, 209, 210,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1V8D

B:1V8D

C:1V8D

D:1V8D

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1V8D.ali
atm file:	1V8D.atm
cof file:	1V8D.cof
hbd file:	1V8D.hbd
html file:	1V8D.html
pdb file:	1V8D.pdb
ps file:	1V8D.ps
psa file:	1V8D.psa
rtf file:	1V8D.rtf
sst file:	1V8D.sst
tem file:	1V8D.tem