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Pfam Domains mapped on to the structure: 1V8B

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 A PF05221 S-adenosyl-L-homocysteine hydrolase PF05221 PF05221
2 A PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PF00670 PF00670
3 A PF07991 Acetohydroxy acid isomeroreductase, catalytic domain PF07991 PF07991

Conserved Domain Database Superfamily Annotations: 1V8B

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 1V8B 29522 cd00401 AdoHcyase - cl09931
2 1V8B 212616 cl09931 NADB_Rossmann superfamily - -
3 1V8B 212616 cl09931 NADB_Rossmann superfamily - -
Structural Details of PDB entry 1V8B

Structural Details of PDB entry 1V8B

PDBid Chains Hinge Swapped Domain
1V8B A,B A:450-458,B:450-458 A:459-479,B:459-479

Swapped-domain interface residues and interactions:

Chains Residues
A 289, 322, 323, 459, 460, 463, 464, 465, 472, 473, 474, 475, 476, 477, 478,
B 289, 322, 323, 459, 460, 463, 464, 465, 472, 473, 474, 475, 476, 477, 478,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 206, 209, 210, 226, 228, 231, 232, 233, 237, 240, 266, 267, 270, 286, 287, 288, 290, 291, 292, 293, 294, 295, 297, 298, 299, 302, 303, 304, 305, 308, 321, 324, 327, 345, 401, 402, 405, 432, 439, 442, 443, 446, 449, 450, 451, 452, 453, 454, 456, 457,
B 206, 209, 210, 226, 228, 231, 232, 233, 237, 240, 266, 267, 270, 286, 287, 288, 290, 291, 292, 293, 294, 295, 297, 298, 299, 303, 304, 305, 308, 321, 324, 327, 345, 401, 402, 405, 432, 439, 442, 443, 446, 449, 450, 451, 452, 453, 454, 456, 457,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
ANo mutationNo mutationNo mutationNo mutation
BNo mutationNo mutationNo mutationNo mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

A:1V8B B:1V8B

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:1V8B.ali
atm file:1V8B.atm
cof file:1V8B.cof
hbd file:1V8B.hbd
html file:1V8B.html
pdb file:1V8B.pdb
ps file:1V8B.ps
psa file:1V8B.psa
rtf file:1V8B.rtf
sst file:1V8B.sst
tem file:1V8B.tem