Pfam Domains mapped on to the structure: 1UXN

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00171	Aldehyde dehydrogenase family	PF00171	PF00171
2	A	PF05893	Acyl-CoA reductase (LuxC)	PF05893	PF05893

Gene Ontology Annotations: 1UXN

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0055114	oxidation-reduction process	GO:0055114

Conserved Domain Database Superfamily Annotations: 1UXN

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1UXN	143401	cd07082	ALDH_F11_NP-GAPDH -	cl11961
2	1UXN	212336	cl11961	ALDH-SF	superfamily - -
3	1UXN	212336	cl11961	ALDH-SF	superfamily - -

Structural Details of PDB entry 1UXN PDBid Chains Hinge Swapped Domain 1UXN A,B A:127-131,B:127-131;A:155-160,B:155-160 A:132-154,B:132-154 Swapped-domain interface residues and interactions: Chains Residues A 132, 136, 138, 140, 142, 143, 145, 146, 149, 151, 153, 154, 460, B 132, 136, 138, 140, 142, 143, 145, 146, 149, 151, 153, 154, 460, Non-swapped-domain interface residues and interactions: Chains Residues A 68, 69, 72, 73, 125, 128, 131, 156, 157, 158, 234, 249, 252, 253, 254, 255, 256, 257, 258, 259, 264, 280, 284, 430, 435, 436, 439, 440, 441, 443, 444, 445, 446, 447, 448, 449, 450, 451, 454, 459, 461, 465, 467, 469, 470, 471, 472, 477, 480, 484, 485, 486, 487, 488, 489, 490, 491, 493, 495, 501, B 68, 69, 72, 73, 125, 128, 131, 156, 157, 158, 234, 249, 252, 253, 254, 255, 256, 257, 258, 259, 264, 280, 284, 430, 435, 436, 439, 440, 441, 443, 444, 445, 446, 447, 448, 449, 450, 451, 454, 459, 461, 465, 467, 469, 470, 471, 472, 477, 480, 484, 485, 486, 487, 488, 489, 490, 491, 493, 495,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1UXN

B:1UXN

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1UXN.ali
atm file:	1UXN.atm
cof file:	1UXN.cof
hbd file:	1UXN.hbd
html file:	1UXN.html
pdb file:	1UXN.pdb
ps file:	1UXN.ps
psa file:	1UXN.psa
rtf file:	1UXN.rtf
sst file:	1UXN.sst
tem file:	1UXN.tem