3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1USP

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF02566 OsmC-like protein PF02566 PF02566

2 B PF02566 OsmC-like protein PF02566 PF02566

Gene Ontology Annotations: 1USP

No. GO ID GO Description Linkout - AmiGO

1 GO:0006950 response to stress GO:0006950

Conserved Domain Database Superfamily Annotations: 1USP

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1USP 212240 cl00767 OsmC superfamily - -

Structural Details of PDB entry 1USP

Structural Details of PDB entry 1USP

PDBid Chains Hinge Swapped Domain

1USP A,B A:22-30,B:22-30 A:3-21,B:2-21

Swapped-domain interface residues and interactions:

Chains Residues
A 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19, 21, 35, 47, 48, 51, 52, 55, 56, 59, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86,

B 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19, 21, 35, 47, 48, 51, 52, 55, 56, 59, 75, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 25, 26, 28, 30, 33, 40, 41, 42, 43, 44, 45, 46, 49, 50, 53, 57, 64, 68, 87, 90, 91, 92, 93, 94, 95, 120, 122, 123, 125, 126, 127, 128, 130, 131, 139,

B 25, 26, 28, 30, 33, 40, 41, 42, 43, 44, 45, 46, 49, 50, 53, 57, 64, 68, 92, 93, 94, 119, 120, 122, 123, 125, 126, 127, 128, 130, 131,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1USP B:1USP

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1USP.ali
atm file: 1USP.atm
cof file: 1USP.cof
hbd file: 1USP.hbd
html file: 1USP.html
pdb file: 1USP.pdb
ps file: 1USP.ps
psa file: 1USP.psa
rtf file: 1USP.rtf
sst file: 1USP.sst
tem file: 1USP.tem