3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1UIN

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00291 Pyridoxal-phosphate dependent enzyme PF00291 PF00291

Conserved Domain Database Superfamily Annotations: 1UIN

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1UIN 107206 cd01563 Thr-synth_1 - cl00342

2 1UIN 212605 cl00342 Trp-synth-beta_II superfamily - -

3 1UIN 212605 cl00342 Trp-synth-beta_II superfamily - -

Structural Details of PDB entry 1UIN

Structural Details of PDB entry 1UIN

PDBid Chains Hinge Swapped Domain

1UIN A,B A:331-335,B:331-335 A:336-351,B:336-350

Swapped-domain interface residues and interactions:

Chains Residues
A 104, 109, 126, 128, 129, 130, 131, 140, 144, 336, 337, 338, 339, 341, 344, 345, 347, 348, 349, 350, 351,

B 104, 109, 126, 128, 129, 130, 131, 140, 144, 336, 337, 338, 339, 341, 344, 345, 347, 348, 349,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 2, 24, 25, 30, 31, 32, 33, 35, 51, 54, 56, 58, 78, 97, 98, 100, 102, 106, 112, 114, 115, 118, 119, 121, 122, 123, 124, 127, 143, 147, 148, 150, 279, 280, 282, 283, 285, 319, 321, 322, 324, 327, 328, 331, 333, 334,

B 24, 25, 28, 30, 32, 33, 35, 51, 54, 56, 58, 97, 98, 100, 102, 106, 114, 115, 118, 119, 121, 122, 123, 124, 127, 139, 143, 147, 148, 150, 174, 279, 280, 282, 283, 285, 319, 321, 322, 324, 327, 328, 330, 331, 332, 333, 334,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1UIN B:1UIN

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1UIN.ali
atm file: 1UIN.atm
cof file: 1UIN.cof
hbd file: 1UIN.hbd
html file: 1UIN.html
pdb file: 1UIN.pdb
ps file: 1UIN.ps
psa file: 1UIN.psa
rtf file: 1UIN.rtf
sst file: 1UIN.sst
tem file: 1UIN.tem