Pfam Domains mapped on to the structure: 1U8S

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13740	ACT domain	PF13740	PF13740

Conserved Domain Database Superfamily Annotations: 1U8S

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1U8S	153165	cd04893	ACT_GcvR_1 -	cl09141
2	1U8S	208988	cl09141	ACT	superfamily - -
3	1U8S	153141	cd04869	ACT_GcvR_2 -	cl09141
4	1U8S	208988	cl09141	ACT	superfamily - -
5	1U8S	208988	cl09141	ACT	superfamily - -

Structural Details of PDB entry 1U8S PDBid Chains Hinge Swapped Domain 1U8S A,B A:83-91,B:83-91 A:2-82,B:2-82 Swapped-domain interface residues and interactions: Chains Residues A 8, 10, 12, 14, 18, 20, 21, 24, 25, 28, 31, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 47, 49, 51, 76, 78, 80, 82, 83, 84, 85, 86, 105, 108, 111, 112, 115, 121, 122, 123, 124, 125, 126, 127, 128, B 8, 10, 12, 14, 17, 20, 21, 24, 25, 28, 29, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 47, 49, 50, 51, 76, 78, 79, 80, 82, 83, 85, 86, 108, 111, 121, 122, 123, 124, 125, 126, 127, 128, Non-swapped-domain interface residues and interactions: Chains Residues A 95, 103, 107, 180, B 103, 107, 112, 115, 141,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	SER(2)-, LEU(3)-,
B	No mutation	No mutation	No mutation	SER(2)-, LEU(3)-,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1U8S

B:1U8S

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1U8S.ali
atm file:	1U8S.atm
cof file:	1U8S.cof
hbd file:	1U8S.hbd
html file:	1U8S.html
pdb file:	1U8S.pdb
ps file:	1U8S.ps
psa file:	1U8S.psa
rtf file:	1U8S.rtf
sst file:	1U8S.sst
tem file:	1U8S.tem