Pfam Domains mapped on to the structure: 1U2W

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF12840	Helix-turn-helix domain	PF12840	PF12840
2	A	PF01022	Bacterial regulatory protein, arsR family	PF01022	PF01022

Conserved Domain Database Superfamily Annotations: 1U2W

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1U2W	28974	cd00090	HTH_ARSR -	cl00088
2	1U2W	212173	cl00088	HTH	superfamily - -

Structural Details of PDB entry 1U2W PDBid Chains Hinge Swapped Domain 1U2W A,D,C,B A:40-43,D:40-43,C:40-43,B:40-43 A:11-39,D:11-39,C:11-39,B:11-39 Swapped-domain interface residues and interactions: Chains Residues A 12, 14, 16, 17, 19, 20, 21, 23, 24, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 39, 40, 42, 45, 46, 50, 61, 64, 65, 111, 112, 115, B 12, 13, 14, 16, 17, 19, 20, 21, 23, 24, 27, 28, 29, 31, 32, 33, 35, 36, 37, 39, 40, 41, 42, 45, 46, 50, 61, 64, 65, 111, 112, 115, Non-swapped-domain interface residues and interactions: Chains Residues A 49, 53, 54, 57, 58, 60, 83, 84, 101, 103, 104, 106, 107, 108, 110, 113, 114, 116, 117, 119, B 49, 53, 54, 57, 58, 60, 83, 84, 87, 101, 103, 106, 107, 108, 110, 113, 114,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	GLY(11)CYS,
D	No mutation	No mutation	No mutation	GLY(11)CYS,
C	No mutation	No mutation	No mutation	GLY(11)CYS,
B	No mutation	No mutation	No mutation	GLY(11)CYS,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1U2W

B:1U2W

C:1U2W

D:1U2W

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1U2W.ali
atm file:	1U2W.atm
cof file:	1U2W.cof
hbd file:	1U2W.hbd
html file:	1U2W.html
pdb file:	1U2W.pdb
ps file:	1U2W.ps
psa file:	1U2W.psa
rtf file:	1U2W.rtf
sst file:	1U2W.sst
tem file:	1U2W.tem