Pfam Domains mapped on to the structure: 1TZH

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	V	PF00341	Platelet-derived growth factor (PDGF)	PF00341	PF00341
2	A	PF13895	Immunoglobulin domain	PF13895	PF13895
3	A	PF13895	Immunoglobulin domain	PF13895	PF13895
4	A	PF13927	Immunoglobulin domain	PF13927	PF13927
5	A	PF13927	Immunoglobulin domain	PF13927	PF13927
6	A	PF00047	Immunoglobulin domain	PF00047	PF00047
7	B	PF13927	Immunoglobulin domain	PF13927	PF13927

Conserved Domain Database Superfamily Annotations: 1TZH

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1TZH	29041	cd00135	PDGF -	cl00116
2	1TZH	206845	cl00116	PDGF	superfamily - -

Structural Details of PDB entry 1TZH PDBid Chains Hinge Swapped Domain 1TZH W,V W:49-51,V:49-51 W:14-48,V:14-48 Swapped-domain interface residues and interactions: Chains Residues V 14, 15, 16, 17, 20, 21, 23, 24, 29, 30, 32, 48, 49, 51, 53, 58, 59, 62, 76, 77, 78, 79, W 14, 15, 16, 17, 20, 21, 23, 24, 29, 30, 32, 48, 49, 51, 53, 58, 59, 62, 76, 77, 78, 79, Non-swapped-domain interface residues and interactions: Chains Residues V 50, 60, 81, 91, 93, 107, W 50, 60, 81, 91, 93,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
W	No mutation	No mutation	No mutation	No mutation
V	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1TZH

W:1TZH

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1TZH.ali
atm file:	1TZH.atm
cof file:	1TZH.cof
hbd file:	1TZH.hbd
html file:	1TZH.html
pdb file:	1TZH.pdb
ps file:	1TZH.ps
psa file:	1TZH.psa
rtf file:	1TZH.rtf
sst file:	1TZH.sst
tem file:	1TZH.tem