Pfam Domains mapped on to the structure: 1TUW

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF04673	Polyketide synthesis cyclase	PF04673	PF04673

Gene Ontology Annotations: 1TUW

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0030639	polyketide biosynthetic process	GO:0030639

Conserved Domain Database Superfamily Annotations: 1TUW

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1TUW	147031	cl04663	Cyclase_polyket	superfamily - -

Structural Details of PDB entry 1TUW PDBid Chains Hinge Swapped Domain 1TUW A,B A:97-100,B:97-100 A:101-107,B:101-107 Swapped-domain interface residues and interactions: Chains Residues A 20, 38, 39, 40, 41, 42, 43, 101, 102, 103, 104, 105, 106, 107, B 20, 38, 39, 40, 41, 42, 43, 101, 102, 103, 104, 105, 106, Non-swapped-domain interface residues and interactions: Chains Residues A 2, 4, 6, 8, 16, 24, 27, 32, 33, 37, 44, 45, 46, 48, 50, 52, 86, 87, 89, 95, 96, 98, 99, 100, B 2, 4, 6, 8, 16, 24, 27, 32, 33, 37, 44, 45, 46, 48, 50, 52, 86, 87, 89, 95, 96, 98, 99, 100,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1TUW

B:1TUW

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1TUW.ali
atm file:	1TUW.atm
cof file:	1TUW.cof
hbd file:	1TUW.hbd
html file:	1TUW.html
pdb file:	1TUW.pdb
ps file:	1TUW.ps
psa file:	1TUW.psa
rtf file:	1TUW.rtf
sst file:	1TUW.sst
tem file:	1TUW.tem