Pfam Domains mapped on to the structure: 1TOH

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00351	Biopterin-dependent aromatic amino acid hydroxylase	PF00351	PF00351

Conserved Domain Database Superfamily Annotations: 1TOH

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1TOH	48241	cd03345	eu_TyrOH -	cl01244
2	1TOH	207351	cl01244	arom_aa_hydroxylase	superfamily - -

Structural Details of PDB entry 1TOH PDBid Chains Hinge Swapped Domain 1TOH A,B A:462-466,B:462-466 A:467-498,B:467-498 Swapped-domain interface residues and interactions: Chains Residues A 450, 454, 455, 456, 457, 459, 470, 471, 472, 473, 476, 478, 479, 480, 481, 482, 483, 485, 486, 487, 489, 490, 492, 493, 494, 496, 497, 498, B 450, 454, 455, 456, 457, 459, 470, 471, 472, 473, 476, 478, 479, 480, 481, 482, 483, 485, 486, 487, 489, 490, 492, 493, 494, 496, 497, Non-swapped-domain interface residues and interactions: Chains Residues A 170, 172, 216, 217, 219, 278, 281, 282, 284, 285, 307, 343, 347, 439, 442, 446, 458, 460, 462, 463, 464, B 170, 172, 216, 217, 219, 278, 281, 282, 284, 285, 307, 343, 347, 439, 442, 446, 458, 460, 462, 463, 464,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1TOH

B:1TOH

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1TOH.ali
atm file:	1TOH.atm
cof file:	1TOH.cof
hbd file:	1TOH.hbd
html file:	1TOH.html
pdb file:	1TOH.pdb
ps file:	1TOH.ps
psa file:	1TOH.psa
rtf file:	1TOH.rtf
sst file:	1TOH.sst
tem file:	1TOH.tem