3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1TMX

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF04444 Catechol dioxygenase N terminus PF04444 PF04444

2 A PF00775 Dioxygenase PF00775 PF00775

Conserved Domain Database Superfamily Annotations: 1TMX

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1TMX 48025 cd03461 1,2-HQD - cl01383

2 1TMX 211449 cl01383 Peptidase_M14NE-CP-C_like superfamily - -

3 1TMX 211449 cl01383 Peptidase_M14NE-CP-C_like superfamily - -

Structural Details of PDB entry 1TMX

Structural Details of PDB entry 1TMX

PDBid Chains Hinge Swapped Domain

1TMX A,B A:72-76,B:72-76 A:2-71,B:2-71

Swapped-domain interface residues and interactions:

Chains Residues
A 3, 8, 9, 12, 13, 16, 19, 20, 22, 23, 24, 26, 27, 28, 31, 32, 35, 36, 38, 39, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 56, 57, 61, 64, 65, 68, 69, 71, 78, 79, 85, 86, 87, 90, 91, 94, 95, 211, 212, 213, 214,

B 6, 9, 12, 13, 16, 19, 20, 23, 24, 26, 27, 28, 31, 32, 34, 35, 36, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 49, 50, 51, 52, 53, 54, 56, 57, 61, 64, 65, 68, 69, 71, 78, 79, 85, 86, 87, 90, 91, 93, 94, 95, 97, 98, 211, 212, 213, 214,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 76, 82, 88, 89, 92, 93, 96, 97, 104, 208, 252, 254, 255, 293,

B 72, 76, 82, 88, 92, 96, 100, 102, 104, 208, 247, 252, 254, 255, 256,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1TMX B:1TMX

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1TMX.ali
atm file: 1TMX.atm
cof file: 1TMX.cof
hbd file: 1TMX.hbd
html file: 1TMX.html
pdb file: 1TMX.pdb
ps file: 1TMX.ps
psa file: 1TMX.psa
rtf file: 1TMX.rtf
sst file: 1TMX.sst
tem file: 1TMX.tem